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1

Mutations in the tyrosine kinase domain of the EGFR gene associated with gefitinib response in non-small-cell lung cancer

Rosell, Rafael, Ichinose, Yukito, Taron, Miquel, Sarries, Carme, Queralt, Cristina, Mendez, Pedro, Sanchez, Jose Miguel, Nishiyama, Ken-ichi, Moran, Teresa, Cirauqui, Beatriz, Mate, Jose Luis, Besse,

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 425 KB

english, 2005

2

Pharmacogenetics and pharmacogenomics as tools in cancer therapy

Rodríguez-Vicente, Ana E., Lumbreras, Eva, Hernández, Jesus M., Martín, Miguel, Calles, Antonio, Otín, Carlos López, Algarra, Salvador Martín, Páez, David, Taron, Miquel

Journal:

Drug Metabolism and Personalized Therapy

Année:

2016

Langue:

english

Fichier:

PDF, 438 KB

english, 2016

3

Isolation of circulating DNA in the serum of cancer patients

Mariano Monzo Planella, Miquel Taron Roca, Pedro Méndez Romero, Rafael Rosell Costa

Journal:

Clinical and Translational Oncology

Année:

2001

Langue:

english

Fichier:

PDF, 32 KB

english, 2001

4

Pharmacogenomic research and serum DNA analysis in the treatment of non-small cell lung cancer

Rafael Rosell, Aurora O'Brate, Mariano Monzó, José Miguel Sánchez, Mónica Guillot, Jacek Jassem, José Javier Sánchez, Albert Abad, Daniel Escuin, Miquel Tarón, Ewa Jassem

Journal:

Clinical and Translational Oncology

Année:

2001

Langue:

english

Fichier:

PDF, 149 KB

english, 2001

5

TRAIL/Apo-2L death signaling pathway and molecular targeting agents: implications for chemoresistance

Rafael Rosell, Hernán Cortés-Funes, Mariano Monzó, Enriqueta Felip, Agustí Barnadas, Miquel Tarón

Journal:

Clinical and Translational Oncology

Année:

2001

Fichier:

PDF, 464 KB

2001

6

Cisplatin plus weekly CPT-11/docetaxel in advanced esophagogastric cancer: a phase I study with pharmacogenetic assessment of XPD, XRCC3 and UGT1A1 polymorphisms

Albert Font, Ramon Salazar, Joan Maurel, Miquel Taron, Jose Luis Ramirez, Josep Tabernero, Rosa Gallego, Esther Casado, Jose Luis Manzano, Enric Carcereny, Marta Guix, Jaume Fernández-Llamazares, Rafa

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 426 KB

english, 2008

7

Pharmacogenetics in lung cancer for the lay doctor

Rafael Rosell, Alain Vergnenegre, Pierre Fournel, Bartomeu Massuti, Carlos Camps, Dolores Isla, Jose Miguel Sanchez, Teresa Moran, Rafael Sirera, Miquel Taron

Journal:

Targeted Oncology

Année:

2008

Langue:

english

Fichier:

PDF, 581 KB

english, 2008

8

From the bench to the bed: individualizing treatment in non-small-cell lung cancer

Mariacarmela Santarpia, Giuseppe Altavilla, Fernanda Salazar, Miquel Tarón, Rafael Rosell

Journal:

Clinical and Translational Oncology

Année:

2006

Langue:

english

Fichier:

PDF, 629 KB

english, 2006

9

Non-small-cell lung cancer harbouring mutations in the EGFR kinase domain

Rafael Rosell, Teresa Morán, Enric Carcereny, Vanessa Quiroga, Miguel Ángel Molina, Carlota Costa, Susana Benlloch, Miquel Tarón

Journal:

Clinical and Translational Oncology

Année:

2010

Langue:

english

Fichier:

PDF, 325 KB

english, 2010

10

Tumour and serumMGMTpromoter methylation and protein expression in glioblastoma patients

Carmen Balañá, Cristina Carrato, José Luis Ramírez, Andrés Felipe Cardona, Mireia Berdiel, José Javier Sánchez, Miquel Tarón, Cristina Hostalot, Eva Musulen, Aurelio Ariza, Rafael Rosell

Journal:

Clinical and Translational Oncology

Année:

2011

Langue:

english

Fichier:

PDF, 491 KB

english, 2011

11

Predictive biomarkers in the management of EGFR mutant lung cancer

Rafael Rosell, Teresa Moran, Felipe Cardenal, Rut Porta, Santiago Viteri, Miguel Angel Molina, Susana Benlloch, Miquel Taron

Journal:

Annals of the New York Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 288 KB

english, 2010

12

FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR

Bivona, Trever G., Hieronymus, Haley, Parker, Joel, Chang, Kenneth, Taron, Miquel, Rosell, Rafael, Moonsamy, Philicia, Dahlman, Kimberly, Miller, Vincent A., Costa, Carlota

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 423 KB

english, 2011

13

Transcripts in pretreatment biopsies from a three-arm randomized trial in metastatic non-small-cell lung cancer

Rosell, Rafael, Scagliotti, Giorgio, Danenberg, Kathleen D, Lord, Reginald VN, Bepler, Gerold, Novello, Silvia, Cooc, Janine, Crinò, Lucio, Sánchez, José Javier, Taron, Miquel

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 134 KB

english, 2003

14

Cytotoxic Effects of Topotecan Combined with Various Active G2/M-Phase Anticancer Drugs in Human Tumor-Derived Cell Lines

Miquel Taron, Carmen Plasencia, Albert Abad, Cristina Martin, Mónica Guillot

Journal:

Investigational New Drugs

Année:

2000

Langue:

english

Fichier:

PDF, 97 KB

english, 2000

15

Antiproliferative effects of ZD0473 (AMD473) in combination with 5-Fluorouracil or SN38 in human colorectal cancer cell lines

Carmen Plasencia, Albert Abad, Eva Martinez-Balibrea, Miquel Taron

Journal:

Investigational New Drugs

Année:

2004

Langue:

english

Fichier:

PDF, 132 KB

english, 2004

16

Biological markers of cisplatin resistance in advanced testicular germ cell tumours

Adelaida García-Velasco, Ignacio Durán, Elena García, Miquel Tarón, Claudio Ballestín, Daniel Castellanos, Hernán Cortés-Funés, Luis Paz-Ares

Journal:

Clinical and Translational Oncology

Année:

2012

Langue:

english

Fichier:

PDF, 712 KB

english, 2012

17

Chemotherapy-Induced Neutropenia Does Not Correlate With DNA Repair Gene Polymorphisms and Treatment Efficacy in Advanced Non–Small-Cell Lung Cancer Patients

Vega Iranzo, Rafael Sirera, Roy M. Bremnes, Ana Blasco, Eloísa Jantus-Lewintre, Miquel Tarón, Alfonso Berrocal, Sara Blasco, Cristina Caballero, Nieves del Pozo, Rafael Rosell, Carlos Camps

Journal:

Clinical Lung Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 546 KB

english, 2011

18

A modified host-cell reactivation assay to quantify DNA repair capacity in cryopreserved peripheral lymphocytes

Pedro Mendez, Miquel Taron, Teresa Moran, Marco A. Fernandez, Gerard Requena, Rafael Rosell

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2011

19

Targeted therapy in combination with gemcitabine in non-small cell lung cancer

Rafael Rosell, Lucio Crino, Kathleen Danenberg, Giorgio Scagliotti, Gerold Bepler, Miquel Taron, Vicente Alberola, Mariano Provencio, Carlos Camps, Filippo De Marinis, Jose Javier Sanchez, Ramon Peñas

Journal:

Seminars in Oncology

Année:

2003

Langue:

english

Fichier:

PDF, 127 KB

english, 2003

20

Molecular predictors of response to chemotherapy in lung cancer

Rafael Rosell, Miquel Taron, Aurelio Ariza, Agusti Barnadas, Jose Luis Mate, Noemı́ Reguart, Mireia Margelı́, Enriqueta Felip, Pedro Méndez, Rosario Garcı́a-Campelo

Journal:

Seminars in Oncology

Année:

2004

Langue:

english

Fichier:

PDF, 153 KB

english, 2004

21

Future Directions in the Second-Line Treatment of Non–Small Cell Lung Cancer

Rafael Rosell, Fabiana Cecere, Francesco Cognetti, Mauricio Cuello, Jose Miguel Sanchez, Miquel Taron, Noemi Reguart, David Jablons

Journal:

Seminars in Oncology

Année:

2006

Langue:

english

Fichier:

PDF, 181 KB

english, 2006

22

Determinants of response and resistance to cytotoxics

Rafael Rosell, Mariano Monzó, Vicente Alberola, Miquel Taron, Agustin Barnadas, Jose Miguel Sánchez, Jose Luis Manzano, José Javier Sanchez

Journal:

Seminars in Oncology

Année:

2002

Langue:

english

Fichier:

PDF, 139 KB

english, 2002

23

Clinical Significance of Hypoxia-Inducible Factor–1α Messenger RNA Expression in Locally Advanced Non–Small-Cell Lung Cancer After Platinum Agent and Gemcitabine Chemotherapy Followed by Surgery

Enriqueta Felip, Miquel Taron, Rafael Rosell, Pedro Mendez, Cristina Queralt, Maria Sanchez Ronco, Jose Javier Sanchez, Jose Miguel Sanchez, Jose Maestre, Joaquim Majo

Journal:

Clinical Lung Cancer

Année:

2005

Langue:

english

Fichier:

PDF, 499 KB

english, 2005

24

Effect of the Methylenetetrahydrofolate Reductase C677T Polymorphism on Patients with Cisplatin/Gemcitabine–Treated Stage IV Non–Small-Cell Lung Cancer

Vicente Alberola, Carme Sarries, Rafael Rosell, Miquel Taron, Ramon de las Peñas, Carlos Camps, Bartomeu Massuti, Amelia Insa, Ramon Garcia-Gomez, Dolores Isla, Angel Artal, Miguel Angel Muñoz, Manuel

Journal:

Clinical Lung Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 149 KB

english, 2004

25

BRCA1: A New Genomic Marker for Non–Small-Cell Lung Cancer

Noemí Reguart, Andrés Felipe Cardona, Esther Carrasco, Patricia Gomez, Miquel Taron, Rafael Rosell

Journal:

Clinical Lung Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 179 KB

english, 2008

26

Circulating MicroRNA Signatures of Tumor-Derived Exosomes for Early Diagnosis of Non–Small-Cell Lung Cancer

Rafael Rosell, Jia Wei, Miquel Taron

Journal:

Clinical Lung Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 63 KB

english, 2009

27

Predicting the outcome of chemotherapy for lung cancer

Rafael Rosell, Fabiana Cecere, Mariacarmela Santarpia, Noemi Reguart, Miquel Taron

Journal:

Current Opinion in Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 316 KB

english, 2006

28

Predicting the outcome of chemotherapy for lung cancer [Current Opinion in Pharmacology 2006, 6:323-331]

Rafael Rosell, Fabiana Cecere, Mariacarmela Santarpia, Neomi Reguart, Miquel Taron

Journal:

Current Opinion in Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 60 KB

english, 2007

29

Biomarkers in lung oncology

Rafael Rosell, Alain Vergnenegre, Baorui Liu, Manuel Cobo, Bartomeu Massuti, Jia Wei, Miguel Angel Molina, Carlota Costa, Cristina Queralt, Miquel Taron

Journal:

Pulmonary Pharmacology & Therapeutics

Année:

2010

Langue:

english

Fichier:

PDF, 429 KB

english, 2010

30

1148 POSTER DAB2 Interactive Protein (DAB2IP) Methylation in Serum DNA of Non-Small-Cell Lung Cancer (NSCLC) Patients (p) With Epidermal Growth Factor Receptor (EGFR) Mutations

J.W. Wei, J.L.R. Jose Luis Ramirez, M.T Miquel Taron, J.J.S. Jose Javier Sanchez, L.C. Laia Capdevila, S.C. Sara Cros, T.M. Teresa Moran, E.C. Enric Carcereny, C.C. Carlos Camps, R.R. Rafael Rosell

Journal:

European Journal of Cancer

Année:

2011

Langue:

english

Fichier:

PDF, 41 KB

english, 2011

31

Expression of choline kinase alpha to predict outcome in patients with early-stage non-small-cell lung cancer: a retrospective study

Ana Ramírez de Molina, Jacinto Sarmentero-Estrada, Cristóbal Belda-Iniesta, Miquel Tarón, Victor Ramírez de Molina, Paloma Cejas, Marcin Skrzypski, David Gallego-Ortega, Javier de Castro, Enrique Casa

Journal:

The Lancet Oncology

Année:

2007

Langue:

english

Fichier:

PDF, 176 KB

english, 2007

32

Drug resistance in non-small cell lung cancer

Monzo, Mariano, Rosell, Rafael, Taron, Miquel

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 186 KB

english, 2001

33

The role of chemotherapy in early non-small-cell lung cancer management

Rosell, Rafael, Felip, Enriqueta, Maestre, Jose, Sanchez, Jose Miguel, Sanchez, Jose Javier, Manzano, Jose Luis, Astudillo, Julio, Taron, Miquel, Monzo, Mariano

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 283 KB

english, 2001

34

DNA repair and cisplatin resistance in non-small-cell lung cancer

Rosell, Rafael, Lord, Reginald V.N, Taron, Miquel, Reguart, Noemi

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 201 KB

english, 2002

35

β-Tubulin mutational analysis: tantalizing findings

Rosell, Rafael, Tarón, Miquel, Sarries, Carme, Queralt, Cristina, Roig, Barbara

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 58 KB

english, 2002

36

Genetic testing for chemotherapy in non-small cell lung cancer

Rosell, Rafael, Taron, Miquel, Alberola, Vicente, Massuti, Bartomeu, Felip, Enriqueta

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 330 KB

english, 2003

37

E-62. Pharmacogenomics: Individualized therapy

Rosell, Rafael, Taron, Miquel, Bepler, Gerold, Alberola, Vicente, Scagliotti, Giorgio

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 121 KB

english, 2003

38

O-43 Ribonucleotide reductase M1 (RRM1) mRNA expression and survival in advanced non-small-cell lung cancer patients treated with gemcitabine plus cisplatin

Rosell, Rafael, Danenberg, Kathleen, Sanchez, Jose Javier, Camps, Carlos, Provencio, Mariano, Isla, Dolores, Diz, Pilar, Artal, Angel, Baron-Duarte, Francisco Javier, Taron, Miquel

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 182 KB

english, 2003

39

P-205 Lack of b-tubulin gene mutations in docetaxel (doc)/cisplatin (cis)-treated stage IV non-small-cell lung cancer (NSCLC) patients (p) at time of tumor progression

Queralt, Cristina, Roig, Barbara, Sarries, Carme, Botia, Monica, Nun˜ez, Laura, Ramirez, JoséLuis, Mendez, Pedro, Sánchez, JoséMiguel, Taron, Miquel, Rosell, Rafael

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 233 KB

english, 2003

40

P-148 ERCC1 and thymidylate synthase expression in malignant pleural mesothelioma

Scagliotti, Giorgio, Rosell, Rafael, Novello, Silvia, Taron, Miquel, Mendez, Pedro, Queralt, Cristina, Caggese, Domenico, Selvaggi, Giovanni

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 375 KB

english, 2003

41

P-225 XPD and RRM1 gene polymorphisms predict gemcitabine (gem)/cisplatin (cis)/docetaxel (doc) outcome in stage III non-small-cell lung cancer (NSCLC): a genetic analysis of the Spanish Lung Cancer Group phase II trial 9901

Sarries, Carme, Garrido, Pilar, Nun˜ez, Laura, Roig, Barbara, Ramirez, Jose Luis, Isla, Dolores, Astudillo, Julio, Sanchez, Jose Javier, Taron, Miquel, Rosell, Rafael

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 178 KB

english, 2003

42

Applications of genomics in NSCLC

Rosella, Rafael, Cobo, Manuel, Isla, Dolores, Miguel Sanchez, Jose, Taron, Miquel, Altavilla, Giuseppe, Santarpia, Mariacarmela, Moran, Teresa, Catot, Silvia, Etxaniza, Olatz

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 726 KB

english, 2005

43

Is there a prognostic role of K-ras point mutations in the serum of patients with advanced non-small cell lung cancer?

Camps, Carlos, Sirera, Rafael, Bremnes, Roy, Blasco, Ana, Sancho, Eva, Bayo, Pilar, Safont, Maria Jose, Sánchez, José Javier, Tarón, Miquel, Rosell, Rafael

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 167 KB

english, 2005

44

Meeting report: 2nd meeting of the European Thoracic Oncology Platform (ETOP)

Stahel, Rolf, Baas, Paul, Faivre-Finn, Corinne, Dooms, Christophe, Passlick, Bernward, Mazières, Julien, Cappuzzo, Federico, Früh, Martin, Sorensen, Jens Benn, Blackhall, Fiona, Taron, Miquel, Gridell

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 355 KB

english, 2010

45

Combined VEGF-A and VEGFR-2 concentrations in plasma: Diagnostic and prognostic implications in patients with advanced NSCLC

Jantus-Lewintre, Eloisa, Sanmartín, Elena, Sirera, Rafael, Blasco, Ana, Sanchez, José Javier, Tarón, Miquel, Rosell, Rafael, Camps, Carlos

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 355 KB

english, 2011

46

Recomendaciones para la determinación de las mutaciones del gen EGFR en el carcinoma de pulmón no microcítico

Jesús García-Foncillas, Pilar Garrido, Javier Gómez, José Palacios, Miquel Tarón

Journal:

Revista Española de Patología

Année:

2011

Fichier:

PDF, 230 KB

2011

47

Role of Genotyping in Non-Small Cell Lung Cancer Treatment

Laura Bonanno, Adolfo Favaretto, Massimo Rugge, Miquel Taron, Dr Rafael Rosell MD

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 197 KB

english, 2011

48

Gene Expression and Polymorphisms of DNA Repair Enzymes: Cancer Susceptibility and Response to Chemotherapy

Carlos Camps, Rafael Sirera, Vega Iranzo, Miquel Tarón, Rafael Rosell

Journal:

Clinical Lung Cancer

Année:

2007

Langue:

english

Fichier:

PDF, 157 KB

english, 2007

49

XPG mRNA Expression Levels Modulate Prognosis in Resected Non–Small-Cell Lung Cancer in Conjunction with BRCA1 and ERCC1 Expression

Roberta Bartolucci, Jia Wei, Jose Javier Sanchez, Laia Perez-Roca, Imane Chaib, Francesco Puma, Raffaele Farabi, Pedro Mendez, Fausto Roila, Tatsuro Okamoto, Miquel Taron, Rafael Rosell

Journal:

Clinical Lung Cancer

Année:

2009

Langue:

english

Fichier:

PDF, 144 KB

english, 2009

50

Can We Customize Chemotherapy? Individualizing Cytotoxic Regimens in Advanced Non–Small-Cell Lung Cancer

Rafael Rosell, Christian Manegold, Teresa Moran, Pilar Garrido, Remei Blanco, Pilar Lianes, Rolf Stahel, Jose Manuel Trigo, Jia Wei, Miquel Taron

Journal:

Clinical Lung Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 343 KB

english, 2008